Why is it that some people never suffer from serious illnesses throughout the year, and even when they do fall ill, they recover quickly?
Behind this, there is no doubt that there is an "invisible special force" within the body - natural killer cells (NK cells).
They are like round-the-clock security officers.
Without any instructions, they can immediately identify and eliminate infected cells and emerging cancer cells.
They serve as the first line of defense against tumor metastasis and viral infections.
This elite force also experienced situations where they ran out of ammunition and supplies.
A significant study published in the top international journal "Cell Reports", titled "Glutathione is Crucial for the Immune Function Mediated by NK Cells", reveals:
The combat power of NK cells is highly dependent on a core antioxidant substance within the body - glutathione (GSH).
Without it, NK cells would quickly become "paralyzed".
Lack of glutathione causes NK cells to "paralyze" instantly
This study utilized gene knockout technology to prevent the NK cells of mice from synthesizing glutathione on their own.
The result is astonishing:
Energy depletion, signal interruption
The absence of glutathione leads to a significant accumulation of reactive oxygen species (ROS, a destructive molecule) within NK cells, impairment of mitochondrial function, and insufficient supply of cellular energy (ATP).
The two key signaling pathways that activate NK cells - mTOR and STAT5 - are blocked, much like soldiers losing their command system.
Proliferation halted, destructive power nullified
Without glutathione, NK cells cannot proliferate or grow normally, nor can they secrete the "weapons" such as granzyme B and interferon-γ that are used to kill viruses.
They became isolated "unarmed" bystanders.
Uncontrolled tumor metastasis
The most crucial point is that in the melanoma lung metastasis model, mice lacking glutathione experienced a significant increase in the number of lung tumor nodules, a decrease in NK cell infiltration, an increase in inhibitory receptors (such as PD-1), and completely lost their control over the metastatic cancer.
Abundant glutathione → Strong NK cells → Effective in preventing cancer metastasis and fighting viruses;
Glutathione deficiency → Exhaustion of NK cells → Loss of immunity, disease progression.
How to effectively replenish glutathione?
The precursor is the key!
Why not just take some glutathione supplements directly?
This is a common misconception.
The directly taken glutathione is a complete tripeptide molecule.
In the gastrointestinal tract, it will be digested and broken down into amino acids, and the amount that can truly enter the cells and exert its function is extremely small.
The scientific approach is: to supplement the precursors of glutathione and allow it to be synthesized autonomously within the cells.
The ABD active factor (an active precursor of glutathione) is currently recognized worldwide as a safe nutritional raw material that can efficiently enter cells and autonomously synthesize GSH.
Clinical verification shows that it can precisely and effectively increase content of glutathione.
The key precursor substance in the ABD active factor - non-free serine - can be directly recognized and taken up by cells.
After entering the cells, it "on demand" synthesizes glutathione, avoiding damage in the gastrointestinal tract.
The results of the double-blind placebo experiment showed that after healthy young people took the ABD active factor (20g/day) for three months, the GSH content in their cells increased by 35.5%, and their muscle activity ability improved by 13%.
Canadian Health Department's authoritative certification to activate immunity
As verified in the research, increasing the intracellular glutathione level can restore the mTOR/STAT5 signaling pathway, allowing the "paralyzed" NK cells to regain their proliferation ability and killing function.
The BD active factor has been certified by the Canadian Health Department and the FDA as the only pure natural GSH precursor substance in the world.
It is certified to have the effect of significantly enhancing human immunity (NPN batch number: 80004370).
Which groups of people are advised to supplement precursors of glutathione?
If you belong to the following groups, you can give priority to using the ABD active factor as a precursor of glutathione to support the function of NK cells:
Have a family history of tumors, or are concerned about cancer prevention and anti-tumor metastasis health care
Often staying up late, under great pressure, and with a significant decline in immunity.
In the post-operative recovery period and with frequent infections
Living in a polluted environment or an environment with smoking or second-hand smoke for a long time
Currently undergoing weight loss (obesity can exacerbate oxidative stress)