RNA - BIO 7

Technology

introduction of multiple modifications in RNA using engineered DNA polymerase variants

Liu Yu’s team Nat Chem | at Shanghai Jiao Tong University used engineered DNA polymerase variants to introduce multiple modifications at specific sites in RNA Using PORDVA innovative technology, fine “pack” RNA There is a growing need for precise position modification of large Rnas in biomedical research and therapeutic applications. These modifications are critical to...

Technology

Bacillus subtilis was modified to achieve efficient biosynthesis of acetoin

Acetoin is an organic compound that is mainly used as a flavor, in the preparation of cream, dairy, yogurt and strawberries, and in organic synthesis. It is widely used in many fields such as food, pharmaceutical and cosmetics. Acetoin is mainly synthesized chemically in industry, but this method relies on non-renewable fossil raw materials, and...

Technology

Using DNA origami to manipulate biofilm structure, precise delivery of macromolecular drugs is realized

Chinese scholars led the team to manipulate the biofilm structure with DNA origami to achieve the precise delivery of macromolecular drugs In the field of biomedicine, how to achieve accurate and efficient delivery of drugs has always been a key problem for scientists to explore. In recent years, with the rapid development of DNA nanotechnology,...