NMN (β-nicotinamide mononucleotide) has received a lot of attention due to its potential antialcoholic and hepatoprotective effects.
Whether it’s a business event or a gathering of friends, drinking alcohol is one of the most unavoidable social events.
Long-term excessive drinking can cause serious damage to the liver, leading to problems such as alcoholic liver disease.
GSHWORLD introduces the scientific basis and application prospect of NMN in treating alcohol and protecting liver.
Mechanism of antialcoholism and liver protection of NMN
Accelerate alcohol metabolism
After drinking alcohol, alcohol is mainly metabolized by the liver and converted into acetaldehyde and acetic acid.
Acetaldehyde is a toxic substance that can cause damage to the liver if not removed in time.
By increasing the level of NAD+, NMN enhances the activity of alcohol dehydrogenase and acetaldehyde dehydrogenase in the liver, accelerates the decomposition and excretion of alcohol and its metabolites, and thus reduces the burden of alcohol on the liver.
Reduce oxidative stress
During the process of alcohol metabolism, a large number of free radicals are produced, which can cause oxidative stress and damage liver cells.
By activating Sirtuins family proteins, NMN enhances the activity of antioxidant enzymes to help clear free radicals, reduce oxidative stress, and protect liver cells from damage.
Promotes liver cell repair
β-Nicotinamide Mononucleotide can promote the proliferation and differentiation of hepatocytes and accelerate the repair process of damaged hepatocytes.
Studies have found that NMN supplementation can significantly improve alcohol-induced liver injury and reduce the occurrence of hepatitis and liver fibrosis.
Regulate inflammation
Alcoholic liver injury is often accompanied by an inflammatory response, leading to the infiltration of liver inflammatory cells and the release of inflammatory factors.
NMN protects liver health by regulating inflammatory signaling pathways, inhibiting inflammatory responses and reducing liver inflammation.
Improve liver function
Long-term drinking can lead to abnormal liver function, such as elevated aminotransferase and fatty liver.
By increasing the level of NAD+, NMN improves the energy metabolism of liver cells, promotes the recovery of liver function, reduces the level of transaminase, and reduces the occurrence of fatty liver.
Conclusion
NMN, as an emerging health supplement, has shown great potential in antialcoholism and liver protection.
No supplement is a substitute for good lifestyle habits.
