In human life activities, NAD (nicotinamide adenine dinucleotide) plays a crucial role. It participates in numerous physiological processes and provides multi-dimensional protection for human health.
NAD⁺ is an important coenzyme in mitochondria that generates the energy molecule ATP, and mitochondria are the “power plants” of cells, catalyzing the production of over 95% of the energy required for life activities.
It can deeply enhance mitochondrial function, convert nutrients into ATP needed by the human body, thereby activating cellular energy and providing power for various body activities.
NAD⁺ is of great significance in anti-aging
It maintains the communication mechanism between the cell nucleus and mitochondria. The weakening of this communication is an important cause of cellular aging.
NAD ⁺ can maintain the normal expression of genes during cell metabolism, keep cells functioning normally, slow down the aging of human cells, and thereby delay the aging of the body.
It can also neutralize free radicals and repair DNA and proteins damaged by oxidation by activating antioxidant enzyme systems such as SOD and glutathione, delay the aging process of cells and protect organ functions.
For metabolism and weight management, NAD⁺ is a key coenzyme in the three major metabolisms of sugar, lipid and protein.
It improves insulin sensitivity by activating the Sirtuins and AMPK pathways, promotes energy conversion, regulates metabolic balance from the root, and helps regulate metabolic weight loss.
In terms of muscle function, NAD⁺ is the core coenzyme for energy metabolism in muscle cells.
It reduces muscle atrophy and enhances muscle endurance and explosive power by activating mitochondrial function and promoting protein synthesis.
Studies have shown that a decline in NAD⁺ levels can lead to sarcopenia and motor function deterioration. Supplementing NAD ⁺ can enhance muscle function and also has a positive effect on improving athletic performance.
Cardiovascular health also cannot do without the protection of NAD⁺
It is a core factor for maintaining heart health. It can prevent and treat cardiovascular diseases and delay heart aging by targeting and activating Sirtuins, regulating energy metabolism, maintaining REDOX homeostasis and regulating inflammatory responses.
In terms of the reproductive system, NAD⁺ participates in the energy metabolism of germ cells and DNA repair, can improve sperm motility and egg quality, and regulate the balance of sex hormones.
Studies have shown that the decline in NAD⁺ levels is closely related to the deterioration of reproductive function, and supplementing NAD⁺ can help delay the aging of the reproductive system.
NAD⁺ can also improve sleep quality
It can help alleviate problems such as anxiety-induced insomnia and light sleep by regulating the expression of core genes of the biological clock and promoting the secretion of melatonin,
while repairing the mitochondrial function of nerve cells and reducing the damage of oxidative stress to the sleep center.
In terms of immune regulation and tumor-assisted suppression, NAD⁺ has the functions of inhibiting leukopenia and regulating immune response.
When used in combination with PD-1 antibody inhibitors,
it can not only reverse the drug resistance of tumor models to immunotherapy,
increase the inhibition rate of tumor cells, but also enhance the protection of heart, liver and kidney functions,
alleviate the toxic reactions caused by radiotherapy and chemotherapy, and promote the recovery of the body.
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