There are some differences in the acceptance of coenzyme Q10 in the public.
For some specific groups of people, appropriate supplementation of coQ10 under the guidance of a doctor may have certain benefits.
According to the results of a global survey by the World Health Organization, only 5% of the world’s truly healthy people, only 20% of the people who have been examined by doctors and diagnosed with illness, and 75% of the people are in a state of sub-health. In the Asian region, the proportion of people in sub-health is higher.
The prevalence rate of cardiovascular diseases in China is still on the rise. It is estimated that 330 million people are suffering from cardiovascular diseases, including 13 million stroke, 11.39 million coronary heart disease, 8.9 million heart failure, 5 million pulmonary heart disease, 4.87 million atrial fibrillation, 2.5 million rheumatic heart disease, 2 million congenital heart disease, 45.3 million peripheral artery disease, and 245 million hypertension.
When it comes to the heart, we have to mention the recently very hot health care product coenzyme Q10.
Statistics of 190,000 samples from the health big Data center show that men are more likely than women to have abnormal indicators of coenzyme Q10.
It can also be confirmed from the side that in cardiovascular and cerebrovascular diseases, men have a higher risk than women, and the risk of severe diseases is indeed higher.
Coenzyme Q10 has adjuvant therapeutic effect on myocardium
Coenzyme Q10 has antioxidant effects
It can reduce the oxidative damage of heart muscle cells caused by inflammation.
Studies have shown that oxidative stress is often present in myocarditis patients’ myocardial tissue, and coenzyme Q10 can effectively fight free radicals and protect cardiomyocytes.
Coq10 provides energy to heart muscle cells
In the state of myocarditis, the energy metabolism of cardiomyocytes may be affected, leading to a decline in myocardial function.
As an energy metabolism product, Coenzyme Q10 can promote the energy production of cardiomyocytes and enhance the contractility and endurance of myocardium.
For example, in some cases of myocarditis, doctors may use a combination of sodium fructose diphosphate oral solution and coenzyme Q10.
Sodium fructose diphosphate oral solution can increase the energy in the heart, so that the damaged myocardial cell membrane quickly recover;
Coenzyme Q10 further promotes cardiomyocyte repair by nourishing the heart.
The effect of medication showed that the symptoms of the patient were alleviated after 1 month of medication, and all indicators were normal after 3 months of review.
What is Coenzyme Q10?
Coenzyme Q10 is a fat-soluble quinone compound in human cells, which plays a crucial role in the energy production process of human cells.
It is an important hydrogen transmitter in the respiratory chain of biological cells, which plays the role of proton transfer and electron transfer in the oxidative respiratory chain of mitochondria, promotes oxidative phosphorylation and the generation of energy carrier ATP, and helps cells convert carbohydrates in food into an important energy molecule ATP.
Coenzyme Q10 is also an antioxidant with obvious anti-lipid peroxidation.
Free radicals are highly reactive chemicals, often containing oxygen atoms, capable of destroying important cellular components, and CoQ10 can effectively fight free radical damage.
Clinically, coenzyme Q10 can be used as an adjunct therapy for a variety of diseases.
For example, it can be used for cardiovascular diseases, such as viral myocarditis, chronic cardiac insufficiency, etc., to provide sufficient oxygen for the heart and protect the heart from sudden heart disease.
For hepatitis, such as viral hepatitis, subacute severe hepatitis, chronic active hepatitis and other auxiliary treatment.
In the comprehensive treatment of cancer, it can alleviate some adverse reactions caused by radiotherapy and chemotherapy.
Coenzyme Q10 supplements
A quarter of CoQ10 in the human blood comes from the diet, including fish, beef, nuts and seeds.
The human body also produces three-quarters of CoQ10.
In March 2019, the State Administration for Market Supervision released the health effects of Coenzyme Q10 for enhancing immunity and antioxidant, and pregnant women are clearly mentioned as unsuitable for the population.
Although coenzyme Q10 has a variety of effects, there may also be some adverse reactions during use, such as stomach upset, loss of appetite, nausea, diarrhea, heart palpitations, rash and so on.
Coq10 should be used under the guidance of a doctor.
Coenzyme Q10 content in the body will peak at the age of 20, and then decline year by year.
Research data show that with the increase of age, the synthesis ability of coenzyme Q10 in the human body gradually decreases.
The content of coenzyme Q10 in cardiac tissue of patients with heart failure was significantly reduced, and the severity of heart failure was related to the degree of coenzyme Q10 deficiency.
Studies have shown that coenzyme Q10 can improve myocardial function and improve cardiovascular disease.
For example, the Q-symbio study was a large, international, multicentre, randomized, double-blind trial that enrolled 420 patients with moderate or severe heart failure, 202 of whom took a daily softgel containing 300mg of Coenzyme Q10 and 212 of whom took a placebo capsule, with a follow-up period of 2 years.
The results showed that after 2 years of intervention, patients had reduced rates of major adverse cardiovascular events, cardiovascular mortality, all-cause mortality, and hospital admissions compared with the placebo group.
Study on Coenzyme Q10
Coq10 may also play a role in other diseases.
A systematic review and dose-response meta-analysis by researchers at Sun Yat-sen University in Shenzhen, published in the Lancet eClinicalMedicine, showed that coQ10 supplementation can help control blood sugar, especially in patients with diabetes, and supplementation of 100 to 200mg per day has the greatest benefit.
In the Nutritional Health Support Position Paper on Heart Failure published by the International Group of Lipid Experts, meta-analyses support that coQ10 supplementation in patients with chronic heart failure (especially at doses ≥200mg/ day), especially in the early stages of heart failure, may help reduce major adverse cardiac events and overall mortality.
Although coenzyme Q10 has been shown in some studies to have a possible adjuvant therapeutic effect on a variety of diseases, the scientific community has not yet reached a clear consensus on its exact health benefits.
The molecular structure of coenzyme Q10 is large, and the absorption rate of the human body is usually only about 3%.
The supplement of coenzyme Q10 should carried out carefully and under the guidance of a doctor.
Why is Coenzyme Q10 popular?
Coq10 is popular for a number of reasons.
With the increase of age, the body’s own ability to synthesize coQ10 gradually declines
Studies have shown that the content of coenzyme Q10 in the body reaches its peak at the age of 20, and then decreases year by year.
This drop in levels can affect the body’s energy production, leading to problems such as decreased physical strength, memory loss, poor color, and may even affect heart function.
Coenzyme Q10 has many benefits for the human body
It can provide power to the heart, often stay up late, work pressure caused by panic, chest tightness and so on have a certain improvement, relieve the discomfort of the heart.
Coenzyme Q10 can also enhance the body’s immunity, through the removal of free radicals in the body, effectively enhance the body’s defense against viruses and germs.
For the human brain, the properties of coenzyme Q10 to promote energy production are conducive to maintaining the vitality of the brain and playing a role in protecting the brain.
In terms of anti-fatigue, coenzyme Q10 can provide energy and oxygen to cells, helping the body to restore vitality and improve energy.
Its antioxidant properties can also help delay the aging of the body and skin, make the body full of vitality, and increase the youthful state.
Coenzyme Q10 helps to reduce the damage of oxidation to sperm and eggs and improve reproductive ability.
Coenzyme Q10 has paid more and more attention and welcomed by more and more people because of its important role in the human body and the characteristics of decreasing content with the increase of age, coupled with its many benefits to the human body and auxiliary therapeutic effect in specific circumstances.
Who is suitable for Coenzyme Q10?
1. Occupational group
Athletes in high-intensity training and competition, energy consumption is huge, the body is easy to fatigue.
Coenzyme Q10 can enhance physical vitality, provide more energy for athletes, and help them to maintain good condition during training and competition.
According to research, Coenzyme Q10 can improve athletes’ endurance and explosive power, reduce fatigue, and promote physical recovery.
Pilots and astronauts work at high altitudes and face special conditions such as low air pressure and low oxygen, which puts a heavy burden on their bodies.
Coenzyme Q10 can help them enhance the body’s adaptability, improve immunity, and reduce the damage to the body.
2. Sick person
Cardiovascular disease patients:
Coenzyme Q10 has a protective effect on the heart, can help improve heart function, and has a certain auxiliary therapeutic effect on patients with cardiovascular diseases such as angina pectoris and heart failure.
Research data show that the content of coenzyme Q10 in cardiac tissue of patients with heart failure significantly reduced, and supplementing Coenzyme Q10 can improve myocardial function and improve cardiovascular disease.
For example, in the Q-symbio study, patients with moderate or severe heart failure who took a soft capsule containing 300mg of coenzyme Q10 had reduced rates of major adverse cardiovascular events, cardiovascular mortality, all-cause mortality, and hospital admissions.
Liver disease patients:
For viral hepatitis, subacute liver necrosis, chronic active hepatitis and other liver disease patients, coenzyme Q10 has an auxiliary therapeutic effect.
It can protect liver cells, promote the regeneration and repair of liver cells, and improve the detoxification function of liver.
Cancer patients and patients undergoing radiotherapy and chemotherapy:
Coenzyme Q10 has antioxidant effects that help fight free radical damage to the body and slow down the aging process.
For cancer patients, coenzyme Q10 can reduce the risk of cancer and has a potential clinical role in preventing tumor growth.
In the comprehensive treatment of cancer, it can alleviate some adverse reactions caused by radiotherapy and chemotherapy.
3. Need to improve the immunity of the population
With the growth of age, the increase of life pressure and the impact of bad living habits, many people’s immunity gradually declined.
Coenzyme Q10 can improve the body’s immunity and enhance the body’s defense against viruses and germs.
It protects cells from oxidative damage by removing free radicals from the body, thus maintaining the normal function of the body.
For people who need to improve immunity and antioxidant, supplementing coenzyme Q10 is a good choice.
The efficacy of Coenzyme Q10
1. Protect the heart
The protective effect of coenzyme Q10 on the heart mainly reflected in providing adequate oxygen to the myocardium and preventing cardiovascular events, especially in the case of myocardial hypoxia.
Studies have shown that coenzyme Q10 can improve the oxygen utilization efficiency of ischemic myocardium, activate myocardial ATP production, and improve cardiac dysfunction.
For example, in the Q-symbio study, patients with moderate or severe heart failure who took soft capsules containing Coenzyme Q10 had reduced rates of major adverse cardiovascular events, cardiovascular mortality, all-cause mortality, and hospital admissions.
Coenzyme Q10 also has an anti-aldosterone effect, which can regulate the electrolyte balance of the heart and reduce the burden on the heart.
2. Protect skin
Coenzyme Q10 can effectively prevent skin aging and reduce facial wrinkles.
It has a powerful antioxidant effect that fights free radicals and reduces the signs of aging.
Coenzyme Q10 can stimulate the production of collagen, increase skin elasticity and improve skin firmness.
It can also provide adequate energy for skin cells, promote the metabolism of skin cells, and make skin more healthy and shiny.
According to research, long-term use of coQ10 can significantly reduce the appearance of facial wrinkles and make the skin look more youthful.
3. anti-fatigue
Coenzyme Q10 keeps the cells in good condition, the body is full of vitality, and has excellent anti-fatigue effect.
It is a natural antioxidant and cell metabolism initiator produced by the cell itself, which can protect and restore the integrity of the biofilm structure, stabilize the membrane potential, and is a non-specific immune enhancer of the body.
Coenzyme Q10 can provide sufficient energy for the cells, so that the cells maintain a good state of health, so that the body is full of vitality, energy, brainpower.
For example, in high-intensity training and competition, coenzyme Q10 supplementation can reduce fatigue and improve endurance and explosive power.
4. anti-cancer
Coenzyme Q10 has anti-tumor effect and can used in the comprehensive treatment of cancer patients.
Studies have shown that coenzyme Q10 can inhibit the growth and spread of tumor cells, enhance the body’s immunity, and reduce the adverse reactions caused by radiotherapy and chemotherapy.
Coq10 acts as an antioxidant to scavenge free radicals and reduce oxidative stress damage to cells, thereby reducing the risk of cancer.
Coq10 can also regulate cell metabolism and promote the apoptosis of tumor cells.
Although the role of coenzyme Q10 in cancer prevention and anti-cancer needs further research and verification, the current study results show that it has certain potential.
